DIYgenomics - the Citizen Genomes Project

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DIYgenomics citizen science experiments

• Direct-to-consumer genomics SNP/locus comparison by condition
• Replicate, extend and develop new studies linking genotype with phenotype/behavior
  • MTHFR mutation, Vitamin B12 deficiency
  • Are you a bad driver? Examine BDNF genotypes and driving records
  • Determine the SNP and genotype profile for Viagra metabolism
  • APOE4 genotyping together with mid-life cholesterol management programs
  • Novelty seeking genotypes together with behavioral data
  • Apply SNP values from the Boston University centenarian study to corresponding phenotypic markers of aging
  • Apply genotype/pharmacogenomic associations found in the PharmGKB database
  • Tie certain genotyping data to environmental data: toxins, stress, etc.
• Apply traditonal economic/financial risk models to multigenic disease risk prediction
• Assemble a list of core SNPs/loci that should be reviewed in any genomics disease analysis

DIYgenomics citizen science ethics and standards

• Citizen science analog of an IRB (institutional review board)/ethics committee for human biomedical research
• Standards development for citizen science
  • Standard means of citizen participation (e.g.; question posing forums)
  • Particpant acknowledgement: Anonymous,Nonanonymous
  • Nomenclature

Personal Genome Analysis Startups

Open science resources

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Contact: m AT melanieswan.com